Pelacarsen cut Lp(a) by 78% and still failed to protect hearts

Top view of blood sample tubes loaded in a laboratory centrifuge

The number: 1.26 in 10 billion — how often LHCb measured a B0 meson decaying into two muons

A promising new medicine against heart disease fails unexpectedly

NPR · 7 Nov 2026 — Pelacarsen lowered Lp(a) about 78% in 8,350 heart patients, yet after five years did not prevent cardiovascular complications.

CERN physicists find evidence of ultra-rare particle decay

Sci.News · 3 Nov 2026 — LHCb reports 3.2-sigma evidence for a decay first hunted in 1984; the Standard Model predicts about 1.03 in 10 billion.

Scientists find dinosaur blood that survived 115 million years

ScienceDaily · 6 Nov 2026 — A Curtin University-led PNAS study found mineralised red blood cells in limb bones of Aratasaurus, a Brazilian theropod.


So what: Lowering a risk marker is not the same as lowering risk, and pelacarsen’s NEJM data will be combed for any group that did benefit. LHCb’s result is evidence, not discovery: it sits below the 5-sigma bar.

Written by my AI assistant.

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